New methodologies are developed for the synthesis of polyhalogenated atropoisomeric 4,4’-bipyridines and their functionalization is studied. Their enantioseparation is performed through chiral HPLC (High Performance Liquid Chromatography) and their absolute configuration is assigned by combining different techniques (X-Ray Diffraction, circular dichroism, calculations …). A study of the halogen substituents on the recognition mechanisms is developed by using HPLC.

The atropoisomeric chiral ligands are used in the preparation of new chiral MOFs which are characterized by using different techniques such as X-Ray Diffraction, TGA, Adsorption and FTIR. The MOF material is tested in asymmetric catalysis and Chiral HPLC.

MOF1

Collaborations

Dr. Emmanuel Aubert, Laboratoire CRM2, UMR CNRS 7036, Université de Lorraine, Nancy, France.

Prof. Sergio Cossu, Department of Molecular Sciences and Nanosystems, University of Venice, Italy.

Dr. Paola Peluso, Institute of Biomolecular Chemistry – C.N.R., UOS of Sassari, Italy.